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15 items for “protein”: records, experiences, guides and model families. Source reports remain distinct from discoveries.

discovery · Source published 2021-07-22

A broader map of human proteins.

Researchers applied AlphaFold to a broad collection of human proteins.

discovery · Source published 2023-07-11

Designing proteins with purpose.

RFdiffusion enabled researchers to generate proteins with specified structural and functional goals.

discovery · Source published 2023-03-16

Predicting a protein’s shape from its sequence

ESMFold applies a protein language model to infer three-dimensional structure directly from an amino-acid sequence, with checkpoints and bulk prediction tools available to researchers.

discovery · Source published 2026-10-08

UW protein designers get more room to test new ideas

A computing grant gives UW researchers more capacity to explore protein designs, with open tools planned and laboratory evidence still essential.

discovery · Source published 2026-10-21

RFD4-Proteina gives researchers a new way to design proteins. The important results begin in the lab.

UW Medicine and NVIDIA have released a protein-design model with code, weights and experimental findings. The opportunity is to help more researchers test useful ideas—with clear limits on what the early evidence establishes.

discovery · Source published 2026-10-09

GSK expands Chai collaboration after testing AI-designed proteins

A reported laboratory evaluation offers an early look at how computer-designed molecules could enter drug research.

discovery · Source published 2021-07-15

Seeing the shape of life.

Researchers used AlphaFold to predict protein structures with accuracy competitive with experimental structures on many CASP14 targets. Bright's interactive p53 view uses a separate, later AlphaFold DB prediction: human p53 AF-P04637-F1 model v6, created on 2025-08-01.

discovery · Source published 2024-05-08

Seeing molecules together.

AlphaFold 3 expanded structural prediction to complexes of proteins and other biomolecules.

discovery · Source published 2024-11-15

Assembling biological model workflows

BioNeMo brings biological foundation models and training components into one framework for protein, molecular, and drug-research experiments.

discovery · Source published 2026-10-20

AI has produced new scorpion-toxin research leads. The next step belongs in the lab.

Anthropic reports 17 protein designs that met its binding criteria. The hopeful story is what researchers can investigate next, not a treatment that already exists.

discovery · Source published 2022-04-27

An enzyme for a plastic problem.

Scientists used machine learning to help engineer an enzyme that breaks down PET plastic.

discovery · Source published 2026-10-22

Carbon-X brings DNA questions into everyday language

Hugging Face’s open model connects genetic sequences with conversational AI. Early benchmarks suggest a cheaper, locally run research tool, while its biological claims still need careful checking.

discovery · Source published 2026-10-20

OpenAI acquires Orchestra Bio: the work between a discovery and a medicine

A promising molecule still needs a path through studies, manufacturing and human decisions. OpenAI’s latest acquisition targets the coordination behind that journey.

discovery · Source published 2026-10-21

NVIDIA’s local AI push brings more work onto your own computer. Here’s what changes.

At GTC Berlin, NVIDIA laid out a range of computers and software for running AI closer to the people using it, from Windows laptops to team-scale workstations. The appealing idea is more control over where data goes and how AI tools work. The test is whether local AI becomes useful and manageable beyond a premium-hardware demo.

collection · Authored Bright experience

Open-Source & Open-Weight AI Models: Compare and Run Locally

Compare 15 AI model families by license, size and openness. Inspect documented local candidates, try a sourced setup guide, and download a dated comparison.